
Read by Bill Gates, Eric Topol

A cardiologist and one of medicine's most-cited researchers, Eric Topol reads at the intersection of science and story, and his book recommendations reflect that vantage. The founder and director of the Scripps Research Translational Institute has flagged 20 titles here, sourced from his Ground Truths Substack, his podcasts, and his Twitter feed. Science and technology lead, joined by society and politics, history, health and wellness, and psychology. Walter Isaacson's The Code Breaker is a top pick; Topol calls it "the best book I've read in years, a page turner, by the master biographer." He praises Michael Lewis's The Premonition and Peter Attia's Outlive, the latter for making "a solid case for insulin resistance to be recognized as a critical condition." From CRISPR to long COVID, his list keeps returning to the frontier where AI, genomics, and medicine meet, a subject of his own writing.
Last updated February 2026 · Every recommendation cited to its original source.
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His 20 recommendations include The Code Breaker, The Premonition, The Song of the Cell, The Coming Wave, and Outlive, concentrating on genomics, artificial intelligence, medicine, and public health.
Walter Isaacson's The Code Breaker is a top pick. Topol calls it "the best book I've read in years, a page turner, by the master biographer," praising its account of CRISPR and genome editing.
They are drawn from his Ground Truths Substack, his podcasts including Ground Truths and Medscape's Medicine and the Machine, and his Twitter/X account, where he shared a top-10 books list for 2019.
Yes. He has authored four titles noted here: The Patient Will See You Now, The Creative Destruction of Medicine, Deep Medicine, and the Textbook of Interventional Cardiology.
He singles out The Coming Wave as "the only AI book that I've read which integrates the two different languages - life science and AI," and his 2019 list included Human Compatible and Artificial Intelligence: A Guide for Thinking Humans.