Skip to content
Eric Topol

What books does Eric Topol recommend?

A cardiologist and one of medicine's most-cited researchers, Eric Topol reads at the intersection of science and story, and his book recommendations reflect that vantage. The founder and director of the Scripps Research Translational Institute has flagged 20 titles here, sourced from his Ground Truths Substack, his podcasts, and his Twitter feed. Science and technology lead, joined by society and politics, history, health and wellness, and psychology. Walter Isaacson's The Code Breaker is a top pick; Topol calls it "the best book I've read in years, a page turner, by the master biographer." He praises Michael Lewis's The Premonition and Peter Attia's Outlive, the latter for making "a solid case for insulin resistance to be recognized as a critical condition." From CRISPR to long COVID, his list keeps returning to the frontier where AI, genomics, and medicine meet, a subject of his own writing.

Last updated February 2026 · Every recommendation cited to its original source.

Eric Topol

Leading voice on AI, genomics, and the democratization of medicine.

The Code Breaker

The Code Breaker

Jennifer Doudna, Gene Editing, and the Future of the Human Race

byWalter Isaacson
2021560 Pages

The best book I've read in years, a page turner, by the master biographer. 🙏 for bringing genetics, genome editing, #CRISPR to the forefront, the life science breakthrough of our era.

Eric Topol

Source: Twitter

The Premonition: A Pandemic Story

byMichael Lewis
2021320 Pages

One of my favorite books this year was Michael Lewis's The Premonition: A Pandemic Story, a page-turner in which he traced the problematic issues of the CDC long before and intra-Covid-19.

Eric Topol

Source: Ground Truths Substack

The Song of the Cell

The Song of the Cell

An Exploration of Medicine and the New Human

bySiddhartha Mukherjee
2022496 Pages

Sid's most recent book, The Song of the Cell, is extraordinary.

Eric Topol

Source: Ground Truths Podcast

The Coming Wave

The Coming Wave

Technology, Power, and the Twenty-first Century's Greatest Dilemma

byMustafa Suleyman, Michael Bhaskar
2023332 Pages

I did wind up taking copious notes when I read it... it's calm, clear-eyed, and levelheaded. It is the only AI book that I've read which integrates the two different languages—life science and AI.

Eric Topol

Source: Ground Truths Substack

Outlive

Outlive

The Science and Art of Longevity

byPeter Attia, Bill Gifford
2023496 Pages

Attia really shines with his knowledge in this area, and it's the best presentation of the data and explainers that I've seen. He makes a solid case for insulin resistance to be recognized as a critical condition.

Eric Topol

Source: Ground Truths Substack

When Breath Becomes Air

byPaul Kalanithi
2016256 Pages

I loved the book and it fully deserved to be the #1 book (non-fiction) in the world. I feel it immortalized Paul.

Eric Topol

Source: American College of Cardiology

The Covenant of Water

byAbraham Verghese
2023736 Pages

I would say masterpiece... We are thrilled to have you.

Eric Topol

Source: Medscape Medicine and the Machine Podcast

Bad Blood: Secrets and Lies in a Silicon Valley Startup

Bad Blood: Secrets and Lies in a Silicon Valley Startup

Secrets and Lies in a Silicon Valley Startup

byJohn Carreyrou
2018352 Pages

The definitive book on the @theranos debacle is John Carreyrou’s 'Bad Blood'. A must-read.

Eric Topol

Source: Twitter

Everything Is Tuberculosis

Everything Is Tuberculosis

The History and Persistence of Our Deadliest Infection

byJohn Green
2025208 Pages

If you want to understand the history of tuberculosis, and why it is still a global scourge, this is the book to read.

Eric Topol

Source: Ground Truths Substack

How Charts Lie

How Charts Lie

Getting Smarter about Visual Information

byAlberto Cairo
2019256 Pages

My top 10 books for 2019.

Eric Topol

Source: Twitter

More from Less

More from Less

The Surprising Story of How We Learned to Prosper Using Fewer Resources—and What Happens Next

byAndrew McAfee
2019352 Pages

My top 10 books for 2019.

Eric Topol

Source: Twitter

Infinite Powers

Infinite Powers

How Calculus Reveals the Secrets of the Universe

bySteven Strogatz
2019384 Pages

My top 10 books for 2019.

Eric Topol

Source: Twitter

You Look Like a Thing and I Love You

You Look Like a Thing and I Love You

How Artificial Intelligence Works and Why It's Making the World a Weirder Place

byJanelle Shane
2019272 Pages

My top 10 books for 2019.

Eric Topol

Source: Twitter

Superior: The Return of Race Science

Superior: The Return of Race Science

The Return of Race Science

byAngela Saini
2019256 Pages

My top 10 books for 2019.

Eric Topol

Source: Twitter

Race After Technology

Race After Technology

Abolitionist Tools for the New Jim Code

byRuha Benjamin
2019172 Pages

My top 10 books for 2019.

Eric Topol

Source: Twitter

Human Compatible

Human Compatible

Artificial Intelligence and the Problem of Control

byStuart Russell
2019352 Pages

My top 10 books for 2019.

Eric Topol

Source: Twitter

Rebooting AI

Rebooting AI

Building Artificial Intelligence We Can Trust

byGary Marcus, Ernest Davis
2019288 Pages

My top 10 books for 2019.

Eric Topol

Source: Twitter

Artificial Intelligence: A Guide for Thinking Humans

byMelanie Mitchell
2019336 Pages

My top 10 books for 2019.

Eric Topol

Source: Twitter

The Long COVID Survival Guide

The Long COVID Survival Guide

How to Take Care of Yourself and What Comes Next

byFiona Lowenstein
2022288 Pages

I'd recommend on #LongCovid

Eric Topol

Source: Twitter

The Long Haul

The Long Haul

How Long Covid Survivors Are Revolutionizing Health Care

byRyan Prior
2022336 Pages

I'd recommend on #LongCovid

Eric Topol

Source: Twitter

Also recommends books in

Frequently asked questions

What books does Eric Topol recommend?

His 20 recommendations include The Code Breaker, The Premonition, The Song of the Cell, The Coming Wave, and Outlive, concentrating on genomics, artificial intelligence, medicine, and public health.

What is Eric Topol's favourite book?

Walter Isaacson's The Code Breaker is a top pick. Topol calls it "the best book I've read in years, a page turner, by the master biographer," praising its account of CRISPR and genome editing.

Where do Eric Topol's book recommendations come from?

They are drawn from his Ground Truths Substack, his podcasts including Ground Truths and Medscape's Medicine and the Machine, and his Twitter/X account, where he shared a top-10 books list for 2019.

Has Eric Topol written any books?

Yes. He has authored four titles noted here: The Patient Will See You Now, The Creative Destruction of Medicine, Deep Medicine, and the Textbook of Interventional Cardiology.

Which books on AI does Eric Topol recommend?

He singles out The Coming Wave as "the only AI book that I've read which integrates the two different languages - life science and AI," and his 2019 list included Human Compatible and Artificial Intelligence: A Guide for Thinking Humans.